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Renowned Surgeon Examines Our Most Significant Contributions To Surgery - From Crude Procedures To Precision Operations
As a result of the scientific advances and medical innovations made in the twentieth century, the United States today occupies an established and unchallenged leading role in the field of surgery. Renowned surgeon Seymour I. Schwartz, MD, gives a sweeping history of American surgical practice in "Gifted Hands: America"s Most Significant Contributions To Surgery" (Prometheus Books). He describes how surgery in the United States has advanced from the comparatively crude practices of pioneering physicians in the pre-Columbian and colonial eras to its current level of preeminence in scientific surgery today.
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Researchers Create Nano-Sized Assassins To Attack Implant Bacteria
Staphylococcus epidermidis is quite an opportunist. Commonly found on human skin, the bacteria pose little danger. But S. epidermidis is a leading cause of infections in hospitals. From catheters to prosthetics, the bacteria are known to hitch a ride on a range of medical devices implanted into patients. Drugshop to buy zoloft online and other pills.
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Lack Of Spectacles Costs $427 Billion
Over 158 million people in the world are effectively blind because they do not have the spectacles they need to correct their vision. The cost of this disability is enormous. A recent study published in the Bull World Health Organ claims that uncorrected refractive error results in a loss of economic productivity globally worth $427 billion.
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Blood-Borne Molecule Helps Regulate Blood-Vessel Integrity

Although maintaining the integrity of blood vessel walls is essential for life, well-controlled temporary leakage of blood contents through the walls of blood vessels into the tissues is a hallmark of inflammation. Although the molecule S1P is known to act on the cells that line blood vessels (endothelial cells) to regulate the permeability of blood vessel walls, the in vivo of SIP in this process remains unknown, and whether it has a role in inflammation has not been determined. In a new study, Shaun Coughlin and colleagues, at UCSF, San Francisco, have shed light on these issues, revealing that mice that lack S1P selectively in plasma (the liquid component of blood) have increased leakage from the blood vessels in response to a variety of stimuli, including inflammatory ones. As the leakage was reversed by treatment with either S1P-containing red blood cells or an agonist for the protein to which SIP binds, the authors conclude that S1P in the blood regulates blood-vessel integrity and prevents potentially lethal decreases in blood volume after exposure to leak-inducing stimuli. TITLE: Sphingosine-1-phosphate in the plasma compartment regulates basal and inflammation-induced vascular leak in mice AUTHOR: Shaun R. Coughlin University of California, San Francisco, San Francisco, USA. View the PDF of this article at: https://www.the-jci.org/article.php?id=38575 Karen Honey Journal of Clinical Investigation JCI online early table of contents: June 15, 2009


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