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Rosiglitazone Does Not Harm Bone Healing If Combined With Metformin In Rats
Taking the diabetes medications metformin and rosiglitazone together reverses the adverse effects on bone of rosiglitazone treatment alone in an experimental model, according to a new study done in rats. The results were presented at The Endocrine Society"s 91st Annual Meeting in Washington, D.C.
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Heavy, Daily Drinking Increases Risk Of High-Grade Prostate Cancer; Makes Preventive Drug Ineffective
Current research is inconclusive regarding the relationship between alcohol consumption and prostate cancer risk. Researchers led by Zhihong Gong Ph.D. of the University of California San Francisco, examined the associations of total alcohol, type of alcoholic beverage, and drinking pattern with risks of total, low- and high-grade prostate cancer. They used data from more than 10,000 men participating in the Prostate Cancer Prevention Trial (PCPT). Drugshop to buy zoloft online and other pills.
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European Food Safety Authority Completes First EU-wide Assessment Of Vitamin And Mineral s Used In Food Supplements
The European Food Safety Authority (EFSA) has completed the first comprehensive assessment of substances used as s of vitamins and minerals in food supplements which are currently sold in the European Union. EFSA has examined 533 applications since 2005, relating to 344 different substances. The assessments were based on scientific evidence provided by food supplement manufacturers to demonstrate the safety of these nutrient s and the extent to which they are absorbed in the body (i.e. their bioavailability).
Medical Devices

Data Shows Incisionless Procedure Reverses Weight Gain

Patients who have regained weight after gastric bypass surgery now have access to an incisionless procedure that appears highly effective at reversing weight gain, according to data presented at the annual meeting of the American Society of Metabolic and Bariatric Surgeons. Santiago Horgan, MD, professor of surgery and director of the Center for the Treatment of Obesity at UC San Diego, presented six-month outcomes from a national registry of 116 patients who underwent the procedure, known as ROSE (Restorative Obesity Surgery, Endolumenal). "We believe this registry represents the largest collection of data showing the effectiveness, safety and durability of the ROSE procedure," said Horgan. "There are not many options to repair a failing gastric bypass. Invasive procedures to restore the anatomy are complicated and risky for most patients. In comparison, there were no significant complications associated with ROSE and most of the patients lost clinically relevant amounts of weight." To perform ROSE, a small, flexible endoscope and tools are inserted through the mouth, down the esophagus, and into the stomach pouch during an outpatient procedure. The tools, developed by USGI Medical Inc., are used to grasp, fold and stitch tissue to reduce both the diameter of the stomach opening and the volume of the stomach pouch. No cuts are made into the patient"s skin. The registry data showed that 88 percent of the patients stopped regaining weight after ROSE. Overall, these 96 patients lost an average 18 percent of their excess weight six months after the procedure. For the purposes of the registry, excess body weight is defined as anything over a body mass index rating of 55. One patient in the study lost 66 pounds or 84 percent of her excess weight during that six-month time period. Patients who were most successful losing weight after their original gastric bypass had the best results following the ROSE procedure. This subset of patients dropped 29 percent of their excess weight during the six months after ROSE. Up to 50 percent of patients who undergo gastric bypass surgery begin to regain weight after two years. This often occurs because the stomach pouch and stoma, the opening to the small intestine, slowly stretch out, allowing the patient to eat more without feeling full. University of California, San Diego


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