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Sen. McConnell Says Filibuster Of Supreme Court Nominee Sotomayor Remains Possible
Appearing on CBS" "Face the Nation" on Sunday, Senate Minority Leader Mitch McConnel (R-Ky.) said that Senate Republicans have not ruled out a filibuster on the Supreme Court nomination of Judge Sonia Sotomayor, The Hill reports. Although McConnell acknowledged that he has "consistently opposed filibustering judges," he added that the "precedent was established" when Democrats filibustered Miguel Estrada, an appeals court nominee under former President George W. Bush. When asked to clarify his statement, McConnell added, "The Democrats have firmly established that as a precedent, but that doesn"t mean you are going to use it" (Blake, The Hill, 6/14). McConnell also said that it is "way too early to be talking about whether or not anybody opposes this nominee" (Schieffer, "Face the Nation," CBS, 6/14).According to The Hill, McConnell is the first top GOP senator to state that a filibuster is a possibility, as most other Republicans have said only that it is too early to determine if it should be an option. Republicans "face a difficult path" if they choose to filibuster Sotomayor because party members have long decried judicial filibusters, The Hill reports (The Hill, 6/14).
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Antibiotic Resistant Bacteria Found In Fertilizer
Vancomycin resistant enterococci (VRE) have been found in sewage sludge, a by-product of waste-water treatment frequently used as a fertilizer. Researchers writing in the open access journal Acta Veterinaria Scandinavica point out the danger of antibiotic resistance genes passing into the human food chain. Drugshop to buy zoloft online and other pills.
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Argenta Discovery Announces Entry Into Phase I For First Candidate From Collaboration With AstraZeneca To Develop Improved Inhaled Bronchodilators
Argenta Discovery Limited, the respiratory drug discovery and development company, announces a major milestone in its joint programme with AstraZeneca aimed at identifying improved inhaled bronchodilators to treat chronic obstructive pulmonary disease (COPD).
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Exploring The Complexity Of Symbiosis In DNA And Cell Biology

The unique association between microorganisms and their hosts, whether insects, plants, or mammals, provides a fascinating view into how microbial symbionts adapt to changing biological environments. Insights into the diversity and complexity of symbiotic relationships are the focus of the current special issue of DNA and Cell Biology, a peer-reviewed journal published by Mary Ann Liebert, Inc. The issue is available free online at http://www.liebertpub.com/dna "Symbiosis is one of the most rapidly growing fields in biology.... After decades of focusing on bacteria in pure culture, it is evident that to manage them for our benefit, we need to understand bacteria in association with the complex biological environments with which they contend in the natural world," write Jo Handelsman, PhD, Editor-in-Chief of DNA and Cell Biology, Professor at the University of Wisconsin-Madison, and President of the Rosalind Franklin Society, and Guest Editor Margaret J. McFall-Ngai, Professor at the University of Wisconsin-Madison, in their Editorial. The issue contains articles representative of the broad range of scientific topics and disciplines related to microbial symbiosis. These include "The Oral Microbial Consortium"s Interaction with the Periodontal Innate Defense System," which describes a process called "local chemokine paralysis," in which the membership and characteristics of the bacterial community that populates the gingival crevice in the human mouth affect the ability of the natural immune defenses in the mouth to detect the presence of harmful bacteria and orchestrate their destruction. Author Richard Darveau, PhD, from the University of Washington in Seattle, describes this phenomenon as "another mechanism by which the action of a single bacterial member of the oral consortium can affect the host responses to a wide variety of different bacteria." The term "symbiont plasticity" describes the mechanisms by which symbiotic microbes adapt to changes in host development, immune responses, and the changing external environment. Jennifer Wernegreen, PhD, from the Marine Biological Laboratory at Woods Hole, MA, and Diana Wheeler, PhD, from the University of Arizona, in Tucson, use the example of mutualism between Blochmannia and their ant hosts to illustrate how the bacteria rely on genetic, ecological, and physiological means to maintain the functional flexibility that allows them to meet the needs of an ant colony rather than the individual ants that make up the colony. Their thought-provoking review of the impact of symbiotic lifestyle on genetic variation and microbial adaptation is entitled, "Remaining Flexible in Old Alliances: Functional Plasticity in Constrained Mutualisms." Adam Silver and Joerg Graf from the University of Connecticut, in Storrs, explore the role of virulence factors and specific toxins produced by members of the Aeromonas veronii bacterial group in the article "Prevalence of Genes Encoding the Type Three Secretion System and the Effectors AexT and AexU in the Aeromonas veronii Group." These bacteria can cause a range of infections, from diarrhea and wound infections to life-threatening septicemia and meningitis. The authors demonstrate the presence of the type-3 secretion factors AexT and AexU in a variety of Aeromonas veronii strains and propose different functions for these two toxins. Vicki Cohn Mary Ann Liebert, Inc./Genetic Engineering News

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