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Ben-Gurion U. Researchers Identify How Stressed Fat Tissue Malfunctions
Ben-Gurion University of the Negev (BGU) researchers, in a collaboration with colleagues from the University of Leipzig, Germany, have identified a signaling pathway that is operational in intra-abdominal fat, the fat depot that is most strongly tied to obesity-related morbidity.
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Terrence Higgins Trust Opens A New HIV And Sexual Health Centre In Nottingham
On 30 July sexual health and HIV charity Terrence Higgins Trust (THT) will officially open its new centre in Nottingham. The charity has been based in the city since February 2008 from its old site in Lace Market. THT"s new centre on 23 Barker Gate, which is funded by NHS Nottingham City, NHS Nottinghamshire County, Nottingham City Council and Nottinghamshire County Council will offer a wider range of services to support people living with HIV and help prevent the rising rates of sexual ill-health. Drugshop to buy zoloft online and other pills.
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Immune Cell Function Can Be Suppressed By Leading Pathogen In Newborns
Group B Streptococcus (GBS), a bacterial pathogen that causes sepsis and meningitis in newborn infants, is able to shut down immune cell function in order to promote its own survival, according to researchers at the University of California, San Diego School of Medicine and the Skaggs School of Pharmacy and Pharmaceutical Sciences. Their study, published online July 13 in the Journal of Experimental Medicine, offers insight into GBS infection - information that may lead to new medical therapies for invasive infectious diseases that affect nearly 3,500 newborns in the United States each year.
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Leicester Geneticists Unearth The Roots Of Human Genetic Variation

A new study at the University of Leicester is using advanced single molecule methods to explore processes that lie at the very core of DNA variation in humans. The study by researcher Shriparna Sarbajna focuses on the process of "recombination", which re-shuffles our genetic content at the time of egg and sperm production. This "re-shuffling" creates new combinations that are passed on to future generations. Ultimately, these new combinations accumulate over many years to generate the patterns of genetic variations seen in contemporary human populations. Doctoral research by Sarbajna uses techniques pioneered by world-renowned geneticist Professor Sir Alec Jeffreys, to analyse human sperm DNA molecules. These techniques are ultimately used to directly understand the nature, location and frequency of changes occurring in our DNA. Sarbajna will be presenting her research at the Festival of Postgraduate Research, which is taking place on Thursday 25th June in the Belvoir Suite, Charles Wilson Building at the University of Leicester between 11.30am and 1pm. Sarbajna said: "These studies are enabling us to explore the very basis of human genetic variation and aiding our understanding of how errors in the process produce pathological changes like those associated with conditions such as alpha thalassaemia and Down syndrome." "Our research has far reaching consequences, ranging from assisting in genetic counselling through identifying factors contributing to infertility and chromosomal abnormalities, to understanding pathogenic rearrangements frequently seen in cancers and some inherited disorders." "Interestingly, understanding how recombination influences patterns of diversity can also shed valuable light into the history and origins of various human populations. Studying recombination is thus, not only of basic scientific importance, but also allows valuable insights into issues ranging from medicine to history and ancestry." "At the heart of the problem is the fact that although vast catalogues of human genetic variation now exist, little is known about the processes that give rise to these in the first place." This research is funded by The Royal Society, the U.K. Medical Research Council and the Louis-Jeantet Foundation. Leicester University


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