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Study Results Present Efficacy And Safety Findings From The PHIRST-1 Study Of Patients With Pulmonary Arterial Hypertension
United Therapeutics Corporation (Nasdaq: UTHR) and Eli Lilly and Company (NYSE: LLY) today announced the results of a pivotal 16-week study showing that a once-daily dose of tadalafil was generally well tolerated, improved exercise capacity and improved time to clinical worsening in patients with pulmonary arterial hypertension (PAH)(1). The randomized, double-blind, 16-week, placebo-controlled Phase 3 study followed 405 patients with PAH, either treatment-naive or taking bosentan, randomized to placebo or tadalafil 2.5 mg, 10 mg, 20 mg or 40 mg orally. Results from the study entitled, "Tadalafil Therapy for Pulmonary Arterial Hypertension," were published in today"s issue of Circulation.
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Democrat Bill, FTC Examine Ways To Drive Down Health Care Costs
A bill introduced Wednesday in the House would create an artificial joints database to root out bad practices and unnecessary surgeries, The New York Times reports. "The bill, co-sponsored by (Democrats) Bill Pascrell Jr. of New Jersey and Lloyd Doggett of Texas, would establish a government-backed registry to track patients" results over time and help detect ineffective surgical practices and faulty devices. Patient registries, in areas like orthopedics, are expected to play an important role in "comparative effectiveness" reviews that the Obama administration hopes will help identify which medical procedures and products work best." Drugshop to buy zoloft online and other pills.
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Developing Gene Therapy To Fight Blindness
An international team of scientists and clinicians from the United States and Saudi Arabia are working to develop gene therapy for treating a rare, hereditary retinal disease. The therapy has been shown to restore lost vision in animal models of retinitis pigmentosa (RP). Their work is being funded in part by a $1.5 million grant from the Prince Salman Center for Disability Research in Saudi Arabia, where the recessive gene mutation that leads to the eye disease RP has been found in children from several families.
Diagnostics

Taking Positions: Some Docs, Businesses Cheer While Others Oppose Effort

As advocacy groups with a stake in health reform take positions in the health reform debate, their battle lines don"t necessarily observe the boundaries of a given sector, industry or professional affiliation. "Business is far from unified in its lobbying efforts for health-care reform," McClatchy/Chicago Tribune reports. "The disparity dilutes its power and may contribute to a plan no faction wants -- or no plan at all." Though everyone agrees cost control is key, other details, such as whether to include an employer mandate, a public health insurance plan, or end the employer-based health insurance system all together, are up in the air. "[W]hile some executives are letting the U.S. Chamber of Commerce or the National Federation of Independent Business express their views in Washington, others are saying those organizations don"t speak for them" (Stafford, 7/20). Meanwhile, the American College of Surgeons backed the House"s version of the health care reform bill, following the lead of the American Medical Association, the Hill reports. "The backing of the physician lobby, which has opposed past reform efforts, would prove incredibly valuable to President Obama and his Democratic allies in their push to enact comprehensive healthcare reform this year." But The Hill also notes that "The house of medicine is far from unified in support of the House Democrats" bill..." Numerous state-based medical societies planned to oppose the overhaul with a letter to lawmakers this week, and the American Association of Neurological Surgeons and the Congress of Neurological Surgeons both announced their disapproval last week (Young, 7/17). This information was reprinted from kaiserhealthnews.org with kind permission from the Henry J. Kaiser Family Foundation. You can view the entire Kaiser Daily Health Policy Report, search the archives and sign up for email delivery at kaiserhealthnews.org. © Henry J. Kaiser Family Foundation. All rights reserved.


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