AIDS Vaccine Day, May 18, marks the occasion in 1997 when U.S. President Bill Clinton challenged researchers to come up with an AIDS vaccine within the following decade, stating that such a vaccine was the only way to eliminate the threat of AIDS. Twelve years later, the goal of an effective HIV vaccine remains unfulfilled, but the need for one remains urgent. AIDS is the number four killer in the world and number one in sub-Saharan Africa. Despite education and prevention campaigns, every day 7,500 people become infected with HIV. Antiretroviral drugs can prolong the lives of those who are infected, but they are not cures, and because of their cost and logistical difficulties, they reach only a minority of those who need them. And for every two individuals who go on antiretroviral treatment, five become HIV infected. As with any major viral pandemic, a vaccine remains the best hope of ending, and not just mitigating, AIDS.
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Shire plc has launched a new UK adherence programme, called "Be Active", to support patients who have been prescribed Calcichew D3 Forte (1250mg calcium carbonate and 400IU colecalciferol). Current guidance highlights the importance of calcium and vitamin D supplementation in the elderly at risk of falls and fractures.1 2, 3 However, adherence to calcium and vitamin D supplementation in the UK is low, with 30% of UK patients regularly reporting missing a dose of calcium/vitamin D supplementation.4 This may contribute to more falls and fractures among the elderly 5, 6 and increase the burden on the healthcare system. 7, 8, 9
Researchers at the University of Minnesota and National Institutes of Health have identified a new function for the protein missing in people with the most common and ultimately lethal form of childhood muscular dystrophy.